CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy.
Hoffer L, Saez-Ayala M, Horvath D, Varnek A, Morelli X, Roche P
Laurent Hoffer
Publications
Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors.
Hernandez J, Hoffer L, Coutard B, Querat G, Roche P, Morelli X, Decroly E, Barral K
Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches.
Hoffer L, Muller C, Roche P, Morelli X