Nos dernières publications: Nature Chemistry, Blood, Nat Struct Mol Biol, Blood Cancer Journal, eLife, PNAS

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CD44 regulates epigenetic plasticity by mediating iron endocytosis. Sebastian Müller, Fabien Sindikubwabo, Tatiana Cañeque, Anne Lafon, Antoine Versini, Bérangère Lombard, Damarys Loew, Ting-Di Wu, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Adeline Durand, Céline Vallot, Sylvain Baulande, Nicolas Servant, Raphaël Rodriguez. Nature Chemistry, DOI:10.1038/s41557-020-0513-5
https://doi.org/10.1101/693424

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers.
Fagnan A, Bagger FO, Piqué-Borràs MR, Ignacimouttou C, Caulier A, Lopez C, Robert E, Uzan B, Gelsi-Boyer V, Aid Z, Thirant C, Moll U, Tauchmann S, Kurtovic-Kozaric A, Maciejewski JP, Dierks C, Spinelli O, Salmoiraghi S, Pabst T, Shimoda K, Deleuze V, Lapillonne H, Sweeney C, Mansat-De Mas V, Leite B, Kadri Z, Malinge S, de Botton S, Micol JB, Kile BT, Carmichael CL, Iacobucci I, Mullighan CG, Carroll MP, Valent P, Bernard OA, Delabesse E, Vyas P, Birnbaum D, Anguita E, Garcon L, Soler E, Schwaller J, Mercher T.
Blood. 2020 Apr 29. pii: blood.2019003062.
https://www.ncbi.nlm.nih.gov/pubmed/32350520

SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Takedachi A, Despras E, Scaglione S, Guérois R, Guervilly JH, Blin M, Audebert S, Camoin L, Hasanova Z, Schertzer M, Guille A, Churikov D, Callebaut I, Naim V,Chaffanet M, Borg JP, Bertucci F, Revy P, Birnbaum D, Londoño-Vallejo A,
Kannouche PL and Gaillard PH
Nat Struct Mol Biol, 2020; VOL 27: 438–449
https://www.nature.com/articles/s41594-020-0419-3

A chemogenomic approach to identify personalized therapy for patients with relapse or refractory acute myeloid leukemia: Results of a prospective feasibility study
Vey N, COLLIGNON A, HOSPITAL MA, MONTERSINO C, Courtier F, Charbonnier A, SAILLARD C, INCAN ED, MOHTY B, Guille A, Adélaïde J, Carbuccia N, Garnier S, Mozziconacci MJ, ZEMMOUR C, Pakradouni J, RESTOUIN A, Castellano R, Chaffanet M, Birnbaum D, and Collette Y
Blood Cancer Journal, in press

Human RPA activates BLM’s bidirectional DNA unwinding from a nick.
Qin Z, Bi L, Hou XM, Zhang S, Zhang X, Lu Y, Li M, Modesti M, Xi XG, Sun B.
Elife. 2020 Feb 26;9. pii: e54098. doi: 10.7554/eLife.54098.PMID: 32101168.
https://elifesciences.org/articles/54098

Tetraspanin-6 negatively regulates exosome production.
Ghossoub R, Chéry M, Audebert S, Leblanc R, Egea-Jimenez AL, Lembo F, Mammar S, Le Dez F, Camoin L, Borg JP, Rubinstein E, David G, Zimmermann P.
Proc Natl Acad Sci U S A. 2020 Feb 27. pii: 201922447. doi: 10.1073/pnas.1922447117.
https://www.ncbi.nlm.nih.gov/pubmed/32108028