Philippe Soubeyran

Group leader CR1 INSERM, HDR
Apr 2010 Oncogene

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.

Andrieu C, Taieb D, Baylot V, Ettinger S, Soubeyran P, De-Thonel A, Nelson C, Garrido C, So A, Fazli L, Bladou F, Gleave M, Iovanna JL, Rocchi P

Feb 2010 Cancer letters

CIP4 is a new ArgBP2 interacting protein that modulates the ArgBP2 mediated control of WAVE1 phosphorylation and cancer cell migration.

Roignot J, Taïeb D, Suliman M, Dusetti NJ, Iovanna JL, Soubeyran P

Jun 2008 Cancer research

ArgBP2-dependent signaling regulates pancreatic cell migration, adhesion, and tumorigenicity.

Taieb D, Roignot J, André F, Garcia S, Masson B, Pierres A, Iovanna JL, Soubeyran P

Sep 2020 JCI insight

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

Lan W, Santofimia-Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S, Camoin L, Huang C, Peng L, Jiménez-Alesanco A, Velázquez-Campoy A, Abián O, Lomberk G, Urrutia R, Rizzuti B, Geli V, Soubeyran P, Neira JL, Iovanna J

Nov 2019 Journal of visualized experiments : JoVE

Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations.

Swayden M, Dobric A, Berthois Y, Villalba H, Audebert S, Camoin L, Iovanna J, Soubeyran P

Nov 2019 FASEB journal : official publication of the Federation of American Societies for Experimental Biology

PML hyposumoylation is responsible for the resistance of pancreatic cancer.

Swayden M, Alzeeb G, Masoud R, Berthois Y, Audebert S, Camoin L, Hannouche L, Vachon H, Gayet O, Bigonnet M, Roques J, Silvy F, Carrier A, Dusetti N, Iovanna JL, Soubeyran P

Nov 2019 Cells

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.

Santofimia-Castaño P, Xia Y, Peng L, Velázquez-Campoy A, Abián O, Lan W, Lomberk G, Urrutia R, Rizzuti B, Soubeyran P, Neira JL, Iovanna J

Jan 2019 Frontiers in oncology

Upcoming Revolutionary Paths in Preclinical Modeling of Pancreatic Adenocarcinoma.

Swayden M, Soubeyran P, Iovanna J

Dec 2018 Heliyon

Pancreatic cancer chemo-resistance is driven by tumor phenotype rather than tumor genotype.

Swayden M, Iovanna J, Soubeyran P

Nov 2018 Scientific reports

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.

Santofimia-Castaño P, Lan W, Bintz J, Gayet O, Carrier A, Lomberk G, Neira JL, González A, Urrutia R, Soubeyran P, Iovanna J

Nov 2018 Oncotarget

Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells.

Boudouresque F, Siret C, Dobric A, Silvy F, Soubeyran P, Iovanna J, Lombardo D, Berthois Y

Jul 2018 Oncotarget

Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma.

Molejon MI, Swayden M, Fanale D, Bintz J, Gayet O, Soubeyran P, Iovanna J

Jul 2017 Proceedings of the National Academy of Sciences of the United States of America

Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B.

Santofimia-Castaño P, Rizzuti B, Pey ÁL, Soubeyran P, Vidal M, Urrutia R, Iovanna JL, Neira JL