Protein-protein interaction inhibition (2P2I): fewer and fewer undruggable targets.

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Dec 2009 Combinatorial chemistry & high throughput screening

Protein-protein interaction inhibition (2P2I): fewer and fewer undruggable targets.

Betzi S, Guerlesquin F, Morelli X

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Dec 2009 Cellular and molecular life sciences : CMLS

The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain.

Meerschaert K, Tun MP, Remue E, De Ganck A, Boucherie C, Vanloo B, Degeest G, Vandekerckhove J, Zimmermann P, Bhardwaj N, Lu H, Cho W, Gettemans J

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Dec 2009 Haematologica

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia.

Kosmider O, Gelsi-Boyer V, Ciudad M, Racoeur C, Jooste V, Vey N, Quesnel B, Fenaux P, Bastie JN, Beyne-Rauzy O, Stamatoulas A, Dreyfus F, Ifrah N, de Botton S, Vainchenker W, Bernard OA, Birnbaum D, Fontenay M, Solary E,

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Dec 2009 Medecine sciences : M/S

[The future of antibody fragments, made of a single immunoglobulin domain].

Chames P, Baty D

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Dec 2009 Molecular and cellular biology

Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn.

Brignatz C, Paronetto MP, Opi S, Cappellari M, Audebert S, Feuillet V, Bismuth G, Roche S, Arold ST, Sette C, Collette Y

Dec 2009 Journal of cellular physiology

p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.

Gironella M, Malicet C, Cano C, Sandi MJ, Hamidi T, Tauil RM, Baston M, Valaco P, Moreno S, Lopez F, Neira JL, Dagorn JC, Iovanna JL

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Dec 2009 Biophysical journal

NMR and MD investigations of human galectin-1/oligosaccharide complexes.

Meynier C, Feracci M, Espeli M, Chaspoul F, Gallice P, Schiff C, Guerlesquin F, Roche P

Dec 2009 Molecular microbiology

Distinct beta-clamp interactions govern the activities of the Y family PolIV DNA polymerase.

Wagner J, Etienne H, Fuchs RP, Cordonnier A, Burnouf D

Dec 2009 International journal of molecular sciences

Binding of natural and synthetic polyphenols to human dihydrofolate reductase.

Sánchez-del-Campo L, Sáez-Ayala M, Chazarra S, Cabezas-Herrera J, Rodríguez-López JN

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Nov 2009 mAbs

Bispecific antibodies for cancer therapy: the light at the end of the tunnel?

Chames P, Baty D