CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression.

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Jul 2022 Cancers

CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression.

Boudin L, De Nonneville A, Finetti P, Guittard G, Nunes JA, Birnbaum D, Mamessier E, Bertucci F

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Jul 2022 Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Interpretable Machine Learning Models to Predict the Resistance of Breast Cancer Patients to Doxorubicin from Their microRNA Profiles.

Ogunleye AZ, Piyawajanusorn C, Gonçalves A, Ghislat G, Ballester PJ

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Jul 2022 Communications biology

NUPR1 protects against hyperPARylation-dependent cell death.

Santofimia-Castaño P, Huang C, Liu X, Xia Y, Audebert S, Camoin L, Peng L, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J

Jun 2022 Nature chemical biology

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain.

Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP, Rondard P

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Jun 2022 PLoS genetics

Single strand gap repair: The presynaptic phase plays a pivotal role in modulating lesion tolerance pathways.

Laureti L, Lee L, Philippin G, Kahi M, Pagès V

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May 2022 Cell

XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.

Richart L, Picod-Chedotel ML, Wassef M, Macario M, Aflaki S, Salvador MA, Héry T, Dauphin A, Wicinski J, Chevrier V, Pastor S, Guittard G, Le Cam S, Kamhawi H, Castellano R, Guasch G, Charafe-Jauffret E, Heard E, Margueron R, Ginestier C

May 2022 Journal for immunotherapy of cancer

Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity.

Bernard PL, Delconte R, Pastor S, Laletin V, Costa Da Silva C, Goubard A, Josselin E, Castellano R, Krug A, Vernerey J, Devillier R, Olive D, Verhoeyen E, Vivier E, Huntington ND, Nunes J, Guittard G

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May 2022 Frontiers in cell and developmental biology

A Journey on Extracellular Vesicles for Matrix Metalloproteinases: A Mechanistic Perspective.

Thuault S, Ghossoub R, David G, Zimmermann P

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Apr 2022 JCI insight

TET2 regulates immune tolerance in chronically activated mast cells.

Rigo R, Chelbi R, Agopian J, Letard S, Griffon A, Ghamlouch H, Vernerey J, Ladopoulos V, Voisset E, De Sepulveda P, Guittard G, Nunès JA, Bidaut G, Göttgens B, Weber M, Bernard OA, Dubreuil P, Soucie E

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Apr 2022 The Journal of physiology

Time-limited alterations in cortical activity of a knock-in mice model of KCNQ2-related developmental and epileptic encephalopathy.

Biba N, Becq H, Pallesi-Pocachard E, Sarno S, Granjeaud S, Montheil A, Kurz M, Villard L, Milh M, Santini PL, Aniksztejn L