The CRCM hosts 19 internationally renowned research teams. Their main scientific and medical topics are the molecular basis of oncogenesis and tumor dissemination, as well as the development of innovative therapeutic innovations for breast cancer, pancreatic cancer and hematological malignancies. Our cross-disciplinary and multidisciplinary approach to cancer research is translated into scientific projects exploring the fundamental bases of tumorigenesis from a molecular and functional point of view in integrated experimental models - tumor oncogenes and suppressors, signaling and cellular polarity, regulation of the epigenome, genome instability, DNA repair, cellular stress, tumor-host interactions and anti-tumor immunity - and their applications in new diagnostic and therapeutic strategies for major pathologies of the hospital.
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