Nos publications

Les équipes du CRCM publient chaque année plus de 130 articles de recherche fondamentale, translationnelle et clinique.

En direct

Le Centre de Recherche en Cancérologie de Marseille fête ses 50 ans ! -

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Jun 2022 PLoS genetics

Single strand gap repair: The presynaptic phase plays a pivotal role in modulating lesion tolerance pathways.

Laureti L, Lee L, Philippin G, Kahi M, Pagès V

Jun 2022 Nature chemical biology

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain.

Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP, Rondard P

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Jun 2022 Annals of translational medicine

Sacituzumab govitecan in triple-negative breast cancer.

de Nonneville A, Goncalves A, Mamessier E, Bertucci F

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May 2022 Cell

XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.

Richart L, Picod-Chedotel ML, Wassef M, Macario M, Aflaki S, Salvador MA, Héry T, Dauphin A, Wicinski J, Chevrier V, Pastor S, Guittard G, Le Cam S, Kamhawi H, Castellano R, Guasch G, Charafe-Jauffret E, Heard E, Margueron R, Ginestier C

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May 2022 Frontiers in cell and developmental biology

A Journey on Extracellular Vesicles for Matrix Metalloproteinases: A Mechanistic Perspective.

Thuault S, Ghossoub R, David G, Zimmermann P

May 2022 Journal for immunotherapy of cancer

Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity.

Bernard PL, Delconte R, Pastor S, Laletin V, Costa Da Silva C, Goubard A, Josselin E, Castellano R, Krug A, Vernerey J, Devillier R, Olive D, Verhoeyen E, Vivier E, Huntington ND, Nunes J, Guittard G

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Apr 2022 JCI insight

TET2 regulates immune tolerance in chronically activated mast cells.

Rigo R, Chelbi R, Agopian J, Letard S, Griffon A, Ghamlouch H, Vernerey J, Ladopoulos V, Voisset E, De Sepulveda P, Guittard G, Nunès JA, Bidaut G, Göttgens B, Weber M, Bernard OA, Dubreuil P, Soucie E

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Apr 2022 The Journal of physiology

Time-limited alterations in cortical activity of a knock-in mice model of KCNQ2-related developmental and epileptic encephalopathy.

Biba N, Becq H, Pallesi-Pocachard E, Sarno S, Granjeaud S, Montheil A, Kurz M, Villard L, Milh M, Santini PL, Aniksztejn L

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Apr 2022 ACS chemical biology

Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer.

Ganier L, Betzi S, Derviaux C, Roche P, Dessaux C, Muller C, Hoffer L, Morelli X, Borg JP

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Mar 2022 Cancers

CSPG4 Expression in GIST Is Associated with Better Prognosis and Strong Cytotoxic Immune Response.

de Nonneville A, Finetti P, Picard M, Monneur A, Pantaleo MA, Astolfi A, Ostrowski J, Birnbaum D, Mamessier E, Bertucci F