In their study, Sylvain, Asma and their colleagues investigated the mechanisms of genetic recombination in the yeast Lachancea kluyveri. Their research shows that the inhibition of recombination on part of the chromosome is due to the absence of certain proteins.
This discovery, made by observing the chromosomes under the microscope during meiosis, sheds light on the understanding of sex differentiation in this yeast.
Bertrand Llorente’s team is thus contributing to our knowledge of the regulation of meiotic recombination and the evolution of sex chromosomes.
Legrand S, Saifudeen A, Bordelet H, Vernerey J, Guille A, Bignaud A, Thierry A, Acquaviva L, Gaudin M, Sanchez A, Johnson D, Friedrich A, Schacherer J, Neale MJ, Borde V, Koszul R, Llorente B. Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2312820121.