Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer.

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To better understand the aging of hematopoietic stem cells through a transcriptomic approach at the single cell level -

Feb 2021 Journal of Clinical Investigation

Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer.

Guo Y, Gabola M, Lattanzio R, Paul C, Pinet V, Tang R, Turali H, Bremond J, Longobardi C, Maurizy C, Da Costa Q, Finetti P, Boissière-Michot F, Rivière B, Lemmers C, Garnier S, Bertucci F, Zlobec I, Chebli K, Tazi J, Azar R, Blanchard JM, Sicinski P, Mamessier E, Lemmers B, Hahne M.

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Feb 2021 Clinical Cancer Research

Transcriptomic Analysis of Laser Capture Microdissected Tumors Reveals Cancer- and Stromal-Specific Molecular Subtypes of Pancreatic Ductal Adenocarcinoma.

Birnbaum DJ, Begg SKS, Finetti P, Vanderburg CR, Neyaz A, Kulkarni AS, Hank T, Tai EC, Deshpande V, Bertucci F, Birmbaum D, Lillemoe KD, Warshaw AL, Mino- Kenudson M, Fernandez-Del Castillo C, Ting DT, Liss AS

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Jan 2021 Gut

Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma.

Aoki S, Inoue K, Klein S, Halvorsen S, Chen J, Matsui A, Nikmaneshi MR, Kitahara S, Hato T, Chen X, Kawakubo K, Nia HT, Chen I, Schanne DH, Mamessier E, Shigeta K, Kikuchi H, Ramjiawan RR, Schmidt TC, Iwasaki M, Yau T, Hong TS, Quaas A, Plum PS, Dima S, Popescu I, Bardeesy N, Munn LL, Borad MJ, Sassi S, Jain RK, Zhu AX, Duda DG.

Nov 2020 Frontiers in Oncology

PELICAN-IPC 2015-016/Oncodistinct-003: A Prospective, Multicenter, Open-Label, Randomized, Non-Comparative, Phase II Study of Pembrolizumab in Combination With Neo Adjuvant EC-Paclitaxel Regimen in HER2-Negative Inflammatory Breast Cancer.

Bertucci A, Bertucci F, Zemmour C, Lerebours F, Pierga JY, Levy C, Dalenc F, Grenier J, Petit T, Berline M, Gonçalves A

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Nov 2020 Journal for immunotherapy of cancer

Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma.

Shigeta K, Matsui A, Kikuchi H, Klein S, Mamessier E, Chen IX, Aoki S, Kitahara S, Inoue K, Shigeta A, Hato T, Ramjiawan RR, Staiculescu D, Zopf D, Fiebig L, Hobbs GS, Quaas A, Dima S, Popescu I, Huang P, Munn LL, Cobbold M, Goyal L, Zhu AX, Jain RK, Duda DG

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Nov 2020 The Journal of biological chemistry

The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1.

Platsaki S, Zhou X, Pinan-Lucarré B, Delauzun V, Tu H, Mansuelle P, Fourquet P, Bourne Y, Bessereau JL, Marchot P

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Nov 2020 Oncogene

The Scribble family in cancer: twentieth anniversary.

Santoni MJ, Kashyap R, Camoin L, Borg JP

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Oct 2020 Molecular oncology

In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor.

Ariey-Bonnet J, Carrasco K, Le Grand M, Hoffer L, Betzi S, Feracci M, Tsvetkov P, Devred F, Collette Y, Morelli X, Ballester P, Pasquier E

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Oct 2020 European journal of medicinal chemistry

Lipolytic enzymes inhibitors: A new way for antibacterial drugs discovery.

Cavalier JF, Spilling CD, Durand T, Camoin L, Canaan S

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Oct 2020 Nature chemistry

CD44 regulates epigenetic plasticity by mediating iron endocytosis.

Müller S, Sindikubwabo F, Cañeque T, Lafon A, Versini A, Lombard B, Loew D, Wu TD, Ginestier C, Charafe-Jauffret E, Durand A, Vallot C, Baulande S, Servant N, Rodriguez R