Low cholesterol biosynthesis favors epithelial-to-mesenchymal transition maintenance and influences tumor molecular subtyping and disease-free survival in colon cancer patients

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Jun 2022 Cancer communications

Low cholesterol biosynthesis favors epithelial-to-mesenchymal transition maintenance and influences tumor molecular subtyping and disease-free survival in colon cancer patients

Aulas A, Liberatoscioli ML, Finetti P, Cabaud O, Birnbaum DJ, Usclade L, Birnbaum D, Bertucci F, Mamessier E

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Jun 2022 Annals of translational medicine

Sacituzumab govitecan in triple-negative breast cancer

de Nonneville A, Goncalves A, Mamessier E, Bertucci F

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Jun 2022 PLoS genetics

Single strand gap repair: The presynaptic phase plays a pivotal role in modulating lesion tolerance pathways.

Laureti L, Lee L, Philippin G, Kahi M, Pagès V

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Jun 2022 Nature chemical biology

Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain.

Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP, Rondard P

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Apr 2022 The Journal of physiology

Time-limited alterations in cortical activity of a knock-in mice model of KCNQ2-related developmental and epileptic encephalopathy.

Biba N, Becq H, Pallesi-Pocachard E, Sarno S, Granjeaud S, Montheil A, Kurz M, Villard L, Milh M, Santini PL, Aniksztejn L

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Mar 2022 The EMBO journal

Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.

Gouirand V, Gicquel T, Lien EC, Jaune-Pons E, Da Costa Q, Finetti P, Metay E, Duluc C, Mayers JR, Audebert S, Camoin L, Borge L, Rubis M, Leca J, Nigri J, Bertucci F, Dusetti N, Lucio Iovanna J, Tomasini R, Bidaut G, Guillaumond F, Vander Heiden MG, Vasseur S

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Feb 2022 Oncoimmunology

Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer.

Tapia-Galisteo A, Sánchez Rodríguez Í, Aguilar-Sopeña O, Harwood SL, Narbona J, Ferreras Gutierrez M, Navarro R, Martín-García L, Corbacho C, Compte M, Lacadena J, Blanco FJ, Chames P, Roda-Navarro P, Álvarez-Vallina L, Sanz L

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Jan 2022 Journal of clinical medicine

Exploratory Study on Application of MALDI-TOF-MS to Detect SARS-CoV-2 Infection in Human Saliva.

Costa MM, Martin H, Estellon B, Dupé FX, Saby F, Benoit N, Tissot-Dupont H, Million M, Pradines B, Granjeaud S, Almeras L

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Dec 2021 The Journal of cell biology

iASPP contributes to cell cortex rigidity, mitotic cell rounding, and spindle positioning.

Mangon A, Salaün D, Bouali ML, Kuzmić M, Quitard S, Thuault S, Isnardon D, Audebert S, Puech PH, Verdier-Pinard P, Badache A

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Dec 2021 EMBO molecular medicine

Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma.

Berestjuk I, Lecacheur M, Carminati A, Diazzi S, Rovera C, Prod'homme V, Ohanna M, Popovic A, Mallavialle A, Larbret F, Pisano S, Audebert S, Passeron T, Gaggioli C, Girard CA, Deckert M, Tartare-Deckert S