PDZ scaffolds regulate extracellular vesicle production, composition, and uptake.


The Marseille Cancer Research Center celebrates its 50th anniversary ! -

Photo de profil par défault
Sep 2023 Proceedings of the National Academy of Sciences of the United States of America

PDZ scaffolds regulate extracellular vesicle production, composition, and uptake.

Castro-Cruz M, Hyka L, Daaboul G, Leblanc R, Meeussen S, Lembo F, Oris A, Van Herck L, Granjeaud S, David G, Zimmermann P

Photo de profil par défault
Jul 2023 BMC biology

Population transcriptogenomics highlights impaired metabolism and small population sizes in tree frogs living in the Chernobyl Exclusion Zone.

Car C, Gilles A, Goujon E, Muller MD, Camoin L, Frelon S, Burraco P, Granjeaud S, Baudelet E, Audebert S, Orizaola G, Armengaud J, Tenenhaus A, Garali I, Bonzom JM, Armant O

Photo de profil par défault
Jun 2023 Cancer research

CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer.

Fattori S, Le Roy A, Houacine J, Robert L, Abes R, Gorvel L, Granjeaud S, Rouvière MS, Ben Amara A, Boucherit N, Tarpin C, Pakradouni J, Charafe-Jauffret E, Houvenaeghel G, Lambaudie E, Bertucci F, Rochigneux P, Gonçalves A, Foussat A, Chrétien AS, Olive D

Photo de profil par défault
May 2023 Nature communications

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia.

Saez-Ayala M, Hoffer L, Abel S, Ben Yaala K, Sicard B, Andrieu GP, Latiri M, Davison EK, Ciufolini MA, Brémond P, Rebuffet E, Roche P, Derviaux C, Voisset E, Montersino C, Castellano R, Collette Y, Asnafi V, Betzi S, Dubreuil P, Combes S, Morelli X

Photo de profil par défault
Mar 2023 Matrix biology : journal of the International Society for Matrix Biology

Tonic repression of Collagen I by the Bradykinin receptor 2 in skin fibroblasts.

Wong HH, Seet SH, Bascom CC, Isfort RJ, Bard F

Photo de profil par défault
Mar 2023 Journal of medicinal chemistry

Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach.

Hoffer L, Garcia M, Leblanc R, Feracci M, Betzi S, Ben Yaala K, Daulat AM, Zimmermann P, Roche P, Barral K, Morelli X

Photo de profil par défault
Dec 2022 Clinical cancer research : an official journal of the American Association for Cancer Research

Mass Cytometry Reveals Classical Monocytes, NK Cells, and ICOS+ CD4+ T Cells Associated with Pembrolizumab Efficacy in Patients with Lung Cancer.

Rochigneux P, Lisberg A, Garcia A, Granjeaud S, Madroszyk A, Fattori S, Gonçalves A, Devillier R, Maby P, Salem N, Gorvel L, Chanez B, Gukasyan J, Carroll J, Goldman J, Chretien AS, Olive D, Garon EB

Photo de profil par défault
Oct 2022 The FEBS journal

Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis.

Barelier S, Avellan R, Gnawali GR, Fourquet P, Roig-Zamboni V, Poncin I, Point V, Bourne Y, Audebert S, Camoin L, Spilling CD, Canaan S, Cavalier JF, Sulzenbacher G

Photo de profil par défault
Sep 2022 Journal of cell science

The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins.

Daulat AM, Wagner MS, Audebert S, Kowalczewska M, Ariey-Bonnet J, Finetti P, Bertucci F, Camoin L, Borg JP

Photo de profil par défault
Sep 2022 Cancer medicine

The need to tailor the omission of axillary lymph node dissection to patients with good prognosis and sentinel node micro-metastases.

Houvenaeghel G, de Nonneville A, Chopin N, Classe JM, Mazouni C, Chauvet MP, Reyal F, Tunon de Lara C, Jouve E, Rouzier R, Daraï E, Gimbergues P, Coutant C, Azuar AS, Villet R, Crochet P, Rua S, Bannier M, Cohen M, Boher JM