The Marseille Cancer Research Center celebrates its 50th anniversary ! -

May 2009 Pancreas

Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.


Zion O, Genin O, Kawada N, Yoshizato K, Roffe S, Nagler A, Iovanna JL, Halevy O, Pines M


Chronic pancreatitis is characterized by inflammation and fibrosis. We evaluated the efficacy of halofuginone, an inhibitor of collagen synthesis and myofibroblast activation, in preventing cerulein-induced pancreas fibrosis.

Read the article