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Géraldine Guasch (CRCM) - Publication in Nature Communications -

The Cibi platform offers a wide range of expertise in bioinformatics
(large scale data integration, development of specific analysis)
and develops state-of-the art bioinformatics pipelines.
We also develop custom-made biological databases for data storage and processing.
Ghislain Bidaut, Platform Manager

Skills and Services

  • NGS (Next Generation Sequencing) data analysis and integration (ChIP-Seq, RNA-Seq, single cell RNA-Seq, Genetic Variants analysis for research and cancer diagnostics)
  • Flow and mass cytometry data analysis
  • Proteomics data analysis
  • Bioinformatics pipelines and database development (Python, R, Bioconductor, RShiny, Django, PostgreSQL, etc…)
  • Projects collaboration (INCa, ANR, ARC, etc…)

Our Pipelines

Trainings

  • We would also underline that we are welcoming applications for Master and engineering school internships.
the Team publications
Jan 2017 PloS one

HTS-Net: An integrated regulome-interactome approach for establishing network regulation models in high-throughput screenings.

Rioualen C, Da Costa Q, Chetrit B, Charafe-Jauffret E, Ginestier C, Bidaut G

Jun 2021 Proceedings of the National Academy of Sciences of the United States of America

High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome.

Chretien AS, Devillier R, Granjeaud S, Cordier C, Demerle C, Salem N, Wlosik J, Orlanducci F, Gorvel L, Fattori S, Hospital MA, Pakradouni J, Gregori E, Paul M, Rochigneux P, Pagliardini T, Morey M, Fauriat C, Dulphy N, Toubert A, Luche H, Malissen M, Blaise D, Nunès JA, Vey N, Olive D

Aug 2018 Blood advances

CXCR5 and ICOS expression identifies a CD8 T-cell subset with T features in Hodgkin lymphomas.

Le KS, Amé-Thomas P, Tarte K, Gondois-Rey F, Granjeaud S, Orlanducci F, Foucher ED, Broussais F, Bouabdallah R, Fest T, Leroux D, Yadavilli S, Mayes PA, Xerri L, Olive D

Jul 2017 Oncotarget

NKp30 expression is a prognostic immune biomarker for stratification of patients with intermediate-risk acute myeloid leukemia.

Chretien AS, Fauriat C, Orlanducci F, Rey J, Borg GB, Gautherot E, Granjeaud S, Demerle C, Hamel JF, Cerwenka A, von Strandmann EP, Ifrah N, Lacombe C, Cornillet-Lefebvre P, Delaunay J, Toubert A, Arnoulet C, Vey N, Olive D

Apr 2021 Journal of oral microbiology

Salivette, a relevant saliva sampling device for SARS-CoV-2 detection.

Melo Costa M, Benoit N, Dormoi J, Amalvict R, Gomez N, Tissot-Dupont H, Million M, Pradines B, Granjeaud S, Almeras L