Oct 2009 Arteriosclerosis, thrombosis, and vascular biology

Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury.

Auteurs

Scheiermann C, Colom B, Meda P, Patel NS, Voisin MB, Marrelli A, Woodfin A, Pitzalis C, Thiemermann C, Aurrand-Lions M, Imhof BA, Nourshargh S

Résumé

Junctional adhesion molecule-C (JAM-C) is an adhesion molecule that has multiple roles in inflammation and vascular biology, but many aspects of its functions under pathological conditions are unknown. Here we investigated the role of JAM-C in leukocyte migration in response to ischemia reperfusion (I/R) injury.

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