Feb 2007 Haematologica

New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias.

Auteurs

Murati A, Adélaïde J, Quilichini B, Rémy V, Sainty D, Stoppa AM, Olschwang S, Birnbaum D, Chaffanet M, Mozziconacci MJ

Résumé

The t(8;16)(p11;p13) translocation, associated with poor prognosis acute monocytic leukemia, fuses MYST3 on chromosome region 8p11 to CBP on chromosome region 16p13. Two types of MYST3-CBP and CBP-MYST3 fusion transcripts have been identified in patients. We describe two new types of MYST3-CBP transcripts and a new primer set.

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