Mar 2016 Journal of acquired immune deficiency syndromes (1999)

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1.

Auteurs

Morgand M, Bouvin-Pley M, Plantier JC, Moreau A, Alessandri E, Pace CS, Pancera M, Ho DD, Poignard P, Bjorkman PJ, Mouquet H, Nussenzweig MC, Kwong PD, Baty D, Chames P, Braibant M, Barin F

Résumé

Highly potent broadly neutralizing monoclonal antibodies (bNAbs) have been obtained from individuals infected by HIV-1 group M variants. We analyzed the cross-group neutralization potency of these bNAbs toward non-M primary isolates (PI).

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