V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1.
Auteurs
Morgand M, Bouvin-Pley M, Plantier JC, Moreau A, Alessandri E, Pace CS, Pancera M, Ho DD, Poignard P, Bjorkman PJ, Mouquet H, Nussenzweig MC, Kwong PD, Baty D, Chames P, Braibant M, Barin F
Résumé
Highly potent broadly neutralizing monoclonal antibodies (bNAbs) have been obtained from individuals infected by HIV-1 group M variants. We analyzed the cross-group neutralization potency of these bNAbs toward non-M primary isolates (PI).
Lire l‘article