V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1.
Auteurs
Morgand M, Bouvin-Pley M, Plantier JC, Alessandri E, Pace CS, Pancera M, Ho DD, Poignard P, Bjorkman PJ, Mouquet H, Nussenzweig MC, Kwong PD, Baty D, Chames P, Braibant M, Barin F
Résumé
Highly potent broadly neutralizing monoclonal antibodies (bNAbs) have been obtained from individuals infected by HIV-1 group M variants. We analyzed the cross-group neutralization potency of these bNAbs toward non-M primary isolates (PI).
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