A route to new cancer therapies: the FA pathway is essential in BRCA1- or BRCA2-deficient cells.
Lachaud C, Rouse J
Christophe Lachaud
Responsable d'équipe Chercheur(e) Publications
Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice.
Lachaud C, Slean M, Marchesi F, Lock C, Odell E, Castor D, Toth R, Rouse J
Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability.
Lachaud C, Moreno A, Marchesi F, Toth R, Blow JJ, Rouse J