Pascale Zimmermann

Responsable d'équipe PhD, HDR
Publications
Mar 2020 Proceedings of the National Academy of Sciences of the United States of America

Tetraspanin-6 negatively regulates exosome production.

Ghossoub R, Chéry M, Audebert S, Leblanc R, Egea-Jimenez AL, Lembo F, Mammar S, Le Dez F, Camoin L, Borg JP, Rubinstein E, David G, Zimmermann P

May 2019 Handbook of experimental pharmacology

Lipids in Exosome Biology.

Egea-Jimenez AL, Zimmermann P

Sep 2018 Journal of lipid research

Phospholipase D and phosphatidic acid in the biogenesis and cargo loading of extracellular vesicles.

Egea-Jimenez AL, Zimmermann P

Nov 2017 Proceedings of the National Academy of Sciences of the United States of America

Syntenin mediates SRC function in exosomal cell-to-cell communication.

Imjeti NS, Menck K, Egea-Jimenez AL, Lecointre C, Lembo F, Bouguenina H, Badache A, Ghossoub R, David G, Roche S, Zimmermann P

Jul 2016 Nature communications

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.

Egea-Jimenez AL, Gallardo R, Garcia-Pino A, Ivarsson Y, Wawrzyniak AM, Kashyap R, Loris R, Schymkowitz J, Rousseau F, Zimmermann P

Nov 2016 The Journal of clinical investigation

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness.

Leca J, Martinez S, Lac S, Nigri J, Secq V, Rubis M, Bressy C, Sergé A, Lavaut MN, Dusetti N, Loncle C, Roques J, Pietrasz D, Bousquet C, Garcia S, Granjeaud S, Ouaissi M, Bachet JB, Brun C, Iovanna JL, Zimmermann P, Vasseur S, Tomasini R

Dec 2020 Journal of extracellular vesicles

Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo.

Leblanc R, Kashyap R, Barral K, Egea-Jimenez AL, Kovalskyy D, Feracci M, Garcia M, Derviaux C, Betzi S, Ghossoub R, Platonov M, Roche P, Morelli X, Hoffer L, Zimmermann P