Eddy Pasquier

Responsable d'équipe CRCN CNRS
Jul 2019 eLife

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.

Overman J, Fontaine F, Wylie-Sears J, Moustaqil M, Huang L, Meurer M, Chiang IK, Lesieur E, Patel J, Zuegg J, Pasquier E, Sierecki E, Gambin Y, Hamdan M, Khosrotehrani K, Andelfinger G, Bischoff J, Francois M

Sep 2017 Cancer research

Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy.

Ciccolini J, Barbolosi D, Meille C, Lombard A, Serdjebi C, Giacometti S, Padovani L, Pasquier E, André N

Oct 2020 Molecular oncology

In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor.

Ariey-Bonnet J, Carrasco K, Le Grand M, Hoffer L, Betzi S, Feracci M, Tsvetkov P, Devred F, Collette Y, Morelli X, Ballester P, Pasquier E

Mar 2022 Journal of medicinal chemistry

CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation.

Carrasco K, Montersino C, Derviaux C, Saez-Ayala M, Hoffer L, Restouin A, Castellano R, Casassa J, Roche P, Pasquier E, Combes S, Morelli X, Collette Y, Betzi S

Jul 2019 Journal of global oncology

Metronomic Chemotherapy for Children in Low- and Middle-Income Countries: Survey of Current Practices and Opinions of Pediatric Oncologists.

Revon-Rivière G, Banavali S, Heississen L, Gomez Garcia W, Abdolkarimi B, Vaithilingum M, Li CK, Leung PC, Malik P, Pasquier E, Epelman S, Chantada G, André N

Jun 2019 Biomedical journal

The beta adrenergic receptor antagonist propranolol alters mitogenic and apoptotic signaling in late stage breast cancer.

Montoya A, Varela-Ramirez A, Dickerson E, Pasquier E, Torabi A, Aguilera R, Nahleh Z, Bryan B

Jan 2019 Organic & biomolecular chemistry

Tuning the properties of a cyclic RGD-containing tetrapeptide through backbone fluorination.

Au C, Gonzalez C, Leung YC, Mansour F, Trinh J, Wang Z, Hu XG, Griffith R, Pasquier E, Hunter L

Mar 2018 European respiratory review : an official journal of the European Respiratory Society

Drug repurposing in malignant pleural mesothelioma: a breath of fresh air?

Boyer A, Pasquier E, Tomasini P, Ciccolini J, Greillier L, Andre N, Barlesi F, Mascaux C

Jan 2018 Frontiers in pharmacology

Metronomics: Intrinsic Anakoinosis Modulator?

Nicolas A, Carré M, Pasquier E

Aug 2017 Scientific reports

Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells.

Yee EMH, Brandl MB, Pasquier E, Cirillo G, Kimpton K, Kavallaris M, Kumar N, Vittorio O

May 2017 Trends in cancer

Metronomic Chemotherapy: Direct Targeting of Cancer Cells after all?

André N, Tsai K, Carré M, Pasquier E

Mar 2017 Scientific reports

Akt targeting as a strategy to boost chemotherapy efficacy in non-small cell lung cancer through metabolism suppression.

Le Grand M, Berges R, Pasquier E, Montero MP, Borge L, Carrier A, Vasseur S, Bourgarel V, Buric D, André N, Braguer D, Carré M

Feb 2017 Mathematical biosciences and engineering : MBE

On drug resistance and metronomic chemotherapy: A mathematical modeling and optimal control approach.

Ledzewicz U, Wang S, Schattler H, Andre N, Heng MA, Pasquier E